Description
BPC-157 (Body Protection Compound 157) | 5 mg
Bio Glow Wellness · Research use only
Research use only. Not for human or animal consumption. Bio Glow Wellness supplies this compound to laboratories, universities and independent researchers for in vitro and analytical work. It is not a medicine, a supplement, or a therapeutic product, and it is not sold for any personal use.
About BPC-157
BPC-157 is a synthetic chain of fifteen amino acids. Its sequence matches a short stretch of a larger protein that researchers isolated from human gastric juice and named body protection compound, which is where the abbreviation comes from. The material supplied here is not extracted from tissue. It is assembled residue by residue by solid-phase peptide synthesis, then cleaved, purified and freeze-dried into the powder in the vial.
The peptide has been a fixture of the experimental literature since the 1990s, largely because it holds together in conditions that destroy most peptides of its size. That durability is the reason it keeps appearing in laboratory models of tissue injury and repair, and it is the reason it is stocked as a research reagent rather than as a curiosity.
BPC-157 Explained Simply
Read this first. The section below is written in ordinary language so that a non-specialist can follow what this compound is and where it shows up in the scientific record. It is not medical advice, it is not a claim that the compound does anything in a person or an animal, and it is not a protocol. Bio Glow Wellness sells BPC-157 for laboratory research only.
The short version
A small, unusually stable laboratory peptide that has been studied for decades in cell and animal models of tissue damage. It is sold here as a research chemical, nothing more.
What it actually is
Peptides are short strings of amino acids, the same building blocks that make up proteins, just far fewer of them. BPC-157 is fifteen links long. The sequence was copied from part of a protein found in the human stomach, an environment acidic enough to break apart most of what passes through it. Scientists took an interest in this particular fragment precisely because it survives there. In a laboratory it can be dissolved in water rather than needing a solvent, and it does not fall apart as quickly as comparable peptides, which makes it straightforward to work with at the bench.
Where it turns up in research
- Tendon and ligament cell studies, where published work has looked at how cultured fibroblasts migrate and spread
- Gastrointestinal models, the setting the peptide was originally characterized in
- Angiogenesis research, meaning the formation of new blood vessels in tissue and in culture
- Growth factor signalling, with published attention to the VEGF and FAK pathways
- Nitric oxide system research, where the peptide has been used as a probe in animal models
- Nervous tissue models, a newer and considerably thinner area of the literature
What the published work shows so far
The bulk of what has been published comes from rodent studies and from cells grown in dishes. In those settings, papers report faster closure of experimental wounds, increased movement of connective tissue cells, and changes in the signalling molecules that govern blood vessel growth. Those are real published observations, and they are also the whole of the picture. Rodent and cell-culture results are a starting point for research, not evidence about people. Controlled human trials of BPC-157 are essentially absent from the peer-reviewed record, and Bio Glow Wellness makes no claim about what the compound does in a human being.
Why researchers keep returning to it
Two practical qualities keep this peptide in circulation as a reagent. It is stable enough to handle without special equipment, and it has a long enough publication history that a new experiment can be positioned against existing work. For a laboratory studying tissue repair signalling, that combination makes it a convenient reference compound. Convenience as a reagent is a statement about laboratory practicality and says nothing at all about safety or effect in a living person.
What nobody can claim about BPC-157
- It cannot be described as a treatment, a therapy, or a remedy for any injury, illness or condition.
- It cannot be described as safe or effective for humans. The controlled human evidence that such a statement would require has not been published.
- It cannot be sold, labelled or discussed as a supplement, a food, a cosmetic or a drug.
- Findings from rats, mice or cultured cells cannot be presented as though they apply to people.
- No recovery time, healing rate or outcome of any kind can be promised on the basis of this literature.
- It is not approved by the FDA for any use, and it is banned in sanctioned sport by the World Anti-Doping Agency.
Where the information above comes from
Chemical identifiers on this page come from public chemistry databases. The research summary reflects the general shape of the peer-reviewed literature on this peptide, which is overwhelmingly preclinical. Researchers should read the primary papers themselves rather than relying on any vendor summary, including this one. Purity and content figures for the specific material shipped are on that batch’s Certificate of Analysis, not here.
Physical and Chemical Data
Reference values for BPC-157 (Body Protection Compound 157). Lot-specific results are on the Certificate of Analysis supplied with the batch.
| Molecular formula | C62H98N16O22 |
| Molecular weight | 1,419.6 g/mol |
| Chain length | 15 residues (pentadecapeptide) |
| Sequence | H-Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val-OH |
| CAS number | 137525-51-0 |
| Classification | Synthetic pentadecapeptide corresponding to a partial sequence of a protein identified in human gastric juice |
| Synonyms | Body Protection Compound 157 · PL-14736 · BPC 15 |
| Appearance | White to off-white lyophilized solid |
| Reported solubility | Reported soluble in water and in bacteriostatic water at laboratory working concentrations |
Molecular Design and Stability
The molecule is a linear chain with no disulphide bridges and no ring closure, which is unusual for a peptide that resists degradation as well as this one does. The stability appears to come from the sequence itself. Three prolines sit in a row near the start of the chain, and proline residues force a rigid kink that many of the enzymes responsible for chopping up peptides cannot accommodate. The result is a chain that stays intact in aqueous and acidic conditions long enough to be useful at the bench.
Because no protecting group, carrier or conjugate is involved, what is in the vial is the bare peptide as a freeze-dried solid. That form is the stable one. Once the powder is taken into solution it behaves like any other reconstituted peptide and is best treated as short-lived, which is the reason the handling notes below suggest aliquoting rather than storing a full vial in solution.
Laboratory Applications
Researchers working with this compound have used it to investigate:
- In vitro assays of fibroblast and tendon cell migration
- Rodent models of gastrointestinal mucosal injury
- Vascular and angiogenesis assays, including tube formation work
- Studies of VEGF receptor and focal adhesion kinase signalling
- Nitric oxide pathway experiments in animal models
- Comparative peptide stability and degradation testing
- Analytical method development, where a well-characterized peptide is needed as a reference
These are descriptions of published experimental work. They are not suggestions for what a buyer should do with the material, and they are not evidence of any effect outside the model in which it was observed.
What the Literature Covers
1. Gastrointestinal origin
The earliest body of work sits in the gut, which follows from where the parent protein was found. Published rodent studies describe effects on experimentally induced mucosal lesions and on gastric blood flow. This is the deepest and oldest part of the literature, and it is the context in which the peptide was first characterized.
2. Connective tissue and cell migration
A second cluster of papers examines tendon, ligament and muscle models. Cell-culture work has reported increased outgrowth and migration of tendon fibroblasts, and animal studies have looked at transected tendon healing. These reports are the source of the peptide’s informal reputation, and it is worth being precise that they are animal and dish studies.
3. Blood vessel formation
Several groups have reported effects on angiogenesis, the growth of new vessels. The mechanism most often proposed in these papers runs through VEGF receptor 2 and the nitric oxide system. This is the most mechanistically developed thread in the literature, though the proposed pathway is still described as proposed rather than settled.
4. Nervous system work
A smaller and more recent set of studies looks at peripheral nerve and central nervous system models in rodents. The volume of work here is thin compared with the gut and connective tissue literature, and conclusions drawn from it should be weighted accordingly.
5. The gap in human evidence
Any honest reading of this literature has to end here. Published BPC-157 research is preclinical almost without exception. There is no body of controlled human trials establishing safety, dose or effect, and the compound has no regulatory approval in any jurisdiction. Its presence in the research record is not the same thing as clinical evidence, and the distinction matters.
Batch Documentation
Every shipment is tied to the paperwork for the lot it came from.
- A Certificate of Analysis is supplied for the batch shipped, where one is available for that lot.
- The COA states the analytical methods used and the results for that specific lot. It is the authoritative record for the material in hand.
- Figures on a COA describe one batch only. They are not carried over to other lots and should not be read as a standing specification for the product.
- Testing is performed by an independent third-party analytical laboratory. The laboratory is named on the certificate.
- Published certificates are collected in the Certificate of Analysis library. Our guide to reading a certificate explains what each section reports and what it does not.
Storage and Handling Guidance
General handling practice for lyophilized research peptides:
- Keep the sealed vial cool, dry and out of direct light.
- For anything beyond short-term storage, refrigerate or freeze in line with the handling standard your laboratory already follows for lyophilized material.
- Limit how often a vial is opened and closed. Each cycle exposes the powder to ambient humidity.
- Reconstituted material is generally less stable than the dry powder. Where a study calls for solution, common practice is to aliquot to the working volume rather than store the whole vial in solution.
- Let a refrigerated vial reach room temperature before opening it, so condensation does not form on the contents.
Bio Glow Wellness does not supply reconstitution volumes, concentrations, schedules or any other instruction for administration to a person or an animal. Handling decisions belong to the researcher and to the standards of the facility doing the work.
Common Questions
Can this be used by a person?
No. It is supplied for in vitro laboratory research only. It is not approved for human or veterinary use, it is not a drug or a supplement, and Bio Glow Wellness will not supply it for any other purpose.
What do researchers use BPC-157 for?
It is used as a research tool in studies of tissue repair signalling, blood vessel formation and gastrointestinal models, and as a stable reference peptide in analytical work. What any particular laboratory does with it depends on the study.
Do you provide dosing or reconstitution instructions?
No. Bio Glow Wellness does not publish dosing, administration or protocol guidance of any kind. Study design, handling and safety practice are the responsibility of the researcher and their institution.
Is a Certificate of Analysis included?
Where one is available for the lot shipped, yes. The COA is specific to that batch and reports the methods run and the results obtained for it. Availability varies by lot.
How is the material supplied?
As a white to off-white lyophilized powder in a sealed vial, labelled with the compound name and the vial size. The stated milligram figure is the amount of peptide in the vial. It is a quantity, not a potency or a dose.
Do you ship internationally?
Orders ship within the United States. Buyers outside the United States are responsible for their own import rules, and orders may be declined where the compound is restricted.
Terms of Sale and Disclaimers
- Sold for laboratory research, analytical and in vitro use only.
- Not for human consumption, not for veterinary use, and not for any form of administration to a living subject.
- Not evaluated by the Food and Drug Administration. Nothing on this page is intended to diagnose, treat, cure or prevent any disease or condition.
- No statement on this page is a representation that the compound is safe or effective for any use.
- The purchaser is responsible for meeting every federal, state and local requirement that applies to buying, holding, using and disposing of research compounds, and for confirming the compound is lawful in their jurisdiction before ordering.
- By ordering, the purchaser confirms they are a qualified researcher or are buying on behalf of a research organization.
